CBSE Class 12 Biology Question Bank with Important Questions – Human Reproduction Gametogenesis 2026: The Ultimate Study Guide
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Preparing for the CBSE Class 12 Biology Board Exam 2026 requires more than just reading the textbook; it demands a strategic approach to one of the highest-weightage chapters: Human Reproduction. Within this unit, Gametogenesis stands out as a foundational process that frequently appears in both theory and competitive medical exams.
This comprehensive CBSE Class 12 Biology Question Bank with Important Questions – Human Reproduction Gametogenesis 2026 is designed to provide students with a clear roadmap. We analyze previous years' trends, official marking schemes, and expert insights to ensure you are ready to score a perfect 100 in your science stream.
Understanding Gametogenesis: The Core of Human Reproduction
Gametogenesis is the biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes. In humans, this process is categorized into two distinct pathways:
Spermatogenesis: The production of male gametes (spermatozoa) in the testes.
Oogenesis: The production of female gametes (ova) in the ovaries.
According to the latest 2026 curriculum updates, the "Reproduction" unit carries a significant weightage of 16 marks out of the 70-mark theory paper. Mastering the microscopic anatomy of the testis and ovary alongside these processes is essential for securing high ranks.
Important Concepts in Spermatogenesis
Spermatogenesis begins at puberty due to the increased secretion of the hypothalamic hormone GnRH (Gonadotropin-Releasing Hormone).
Spermatogonia: Diploid (2n) stem cells that multiply by mitosis.
Primary Spermatocytes: Undergo the first meiotic division (reduction division) to form two equal haploid secondary spermatocytes (n).
Secondary Spermatocytes: Undergo the second meiotic division to produce four equal haploid spermatids.
Spermiogenesis: The transformation of non-motile spermatids into motile spermatozoa.
Spermiation: The release of mature sperms from the seminiferous tubules.

Key Highlights of Oogenesis
Unlike spermatogenesis, oogenesis is initiated during the embryonic development stage when a couple of million gamete mother cells (oogonia) are formed within each fetal ovary. No more oogonia are added after birth.
Primary Oocytes: Oogonia that have started prophase-I of meiosis and remain temporarily arrested at that stage.
Follicular Development: Primary oocytes are surrounded by granulosa cells to form primary, secondary, and tertiary follicles.
Ovulation: The secondary oocyte is released from the Graafian follicle upon the rupture of its wall, usually triggered by an LH Surge.
CBSE Class 12 Biology Question Bank with Important Questions – Human Reproduction Gametogenesis 2026
To help you excel, we have curated a list of repeated and high-probability questions based on an analysis of the last 10 years of CBSE board papers.
Very Short Answer Questions (1 Mark)
Question: Why are human testes located outside the abdominal cavity in the scrotum?
Question: Name the enzyme present in the acrosome that helps in fertilization.
Answer: Hyaluronidase.
Question: What is the ploidy level of a secondary spermatocyte?
Answer: Haploid (n).
Short Answer Questions (2 & 3 Marks)
Question: Differentiate between Spermiogenesis and Spermiation.
Question: Explain the role of Pituitary and Ovarian hormones in the process of Oogenesis.
Question: Draw a well-labeled diagram of a human sperm.
Long Answer & Case-Based Questions (4 & 5 Marks)
Question: Describe the various stages of Oogenesis in a human female with the help of a flow chart.
Question: Case Study: A couple is unable to conceive. Medical reports suggest
the male partner has a low sperm count and the sperms show low motility.
(a) Identify the part of the sperm responsible for motility.
(b) Name the hormones that regulate the production of sperms.
Essential Formulas and Statistical Data for 2026
While Biology is primarily theoretical, understanding the quantitative aspects of gametogenesis helps in solving MCQ and Assertion-Reasoning questions.
Sperm Production Ratio
Egg Production Ratio
Semen Composition: A single ejaculation contains 200–300 million sperms. For normal fertility, at least 60% must have normal shape/size and 40% must show vigorous motility.
Important Resources and Links
Official CBSE Question Bank: Access Class 12 Practice Papers
NCERT Textbook PDF: Download Biology Class 12
Swayam Free Courses: Biology Senior Secondary Modules
Conclusion
Mastering the CBSE Class 12 Biology Question Bank with Important Questions – Human Reproduction Gametogenesis 2026 is a surefire way to boost your confidence and your score. By focusing on hormonal pathways, diagram practice, and the differences between male and female gamete formation, you can easily tackle even the most complex competency-based questions.
FAQ: CBSE Class 12 Biology Question Bank with Important Questions – Human Reproduction Gametogenesis 2026
Q1. What is the most important topic in the CBSE Class 12 Biology Question Bank with Important Questions – Human Reproduction Gametogenesis 2026?
The hormonal regulation of both spermatogenesis and oogenesis (role of LH, FSH, and Androgens) and the diagrammatic representation of the female reproductive cycle are the most critical topics for the 2026 boards.
Q2. How many primary follicles are left in each ovary at puberty?
Approximately 60,000 to 80,000 primary follicles are left in each ovary at the time of puberty.
Q3. At what stage is the first meiotic division completed during oogenesis?
The first meiotic division is completed within the tertiary follicle, just prior to ovulation, resulting in a large haploid secondary oocyte and a tiny first polar body.



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