CBSE Class 12 Chemistry Question Bank with Important Questions – Amines Reactions 2026
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Preparing for the CBSE Class 12 Chemistry Question Bank is the ultimate strategy to ace your 2026 board exams. Organic chemistry, specifically the "Amines" chapter, holds significant weightage not just for the board exams but also for competitive medical entrance tests like NEET. Amines are the nitrogen-containing backbones of many life-saving drugs and biological molecules.
In this comprehensive guide, we break down the most repeated reactions, provide a curated question bank for 2026, and explore the medical relevance of these compounds.
1. Why Amines are Critical for CBSE 2026 and Medical Aspirants
Amines are derivatives of ammonia where hydrogen atoms are replaced by alkyl or aryl groups. For a student focusing on the CBSE Class 12 Chemistry Question Bank, understanding the basicity and chemical transformations of amines is non-negotiable.
From a medical perspective, amines are the foundation of:
Neurotransmitters: Adrenaline and Serotonin.
Analgesics: Morphine and Demerol.
Anesthetics: Novocain, widely used in dentistry.
2. Essential Named Reactions in Amines
According to the latest 2026 syllabus trends, the following reactions are frequently featured in the CBSE Class 12 Chemistry Question Bank.
A. Preparation of Amines
Gabriel Phthalimide Synthesis: Used for preparing pure primary aliphatic amines. (Note: This cannot be used for aromatic amines).
Hoffmann Bromamide Degradation Reaction: A key "carbon-shortening" reaction where an amide is converted to a primary amine with one less carbon atom.
Reduction of Nitriles and Nitro Compounds: Using reagents like LiAlH4 or Sn/HCl.
B. Chemical Properties and Identification
Carbylamine Reaction: Also known as the Isocyanide Test. It is used to identify primary amines through the formation of a foul-smelling substance.
Hinsberg’s Test: A vital diagnostic tool in the lab to distinguish between primary, secondary, and tertiary amines using Benzenesulphonyl chloride.
Coupling Reaction: Essential for the synthesis of "Azo Dyes," where diazonium salts react with phenols or anilines to form brightly colored compounds.
3. CBSE Class 12 Chemistry Question Bank: Most Important Questions 2026
Based on the analysis of previous year papers and official sample papers for 2025-26, we have categorized the most likely questions.
Section A: Conceptual & Basic Strength (1-2 Marks)
Arrange the following in increasing order of basic strength in aqueous solution:
(CH3)2NH, CH3NH2, (CH3)3N, NH3.
Why is Aniline a weaker base than Ammonia? (Hint: Resonance delocalization of the lone pair).
Why can’t Aromatic primary amines be prepared by Gabriel Phthalimide Synthesis?
Section B: Conversions and Named Reactions (3 Marks)
How do you convert Nitrobenzene to Aniline?
Identify A, B, and C in reaction:
Explain the role of Pyridine in the acylation of amines.
Section C: Medical & Industrial Applications (Case Study)
Question: A certain amine is used as a precursor for synthesizing antihistamines like Benadryl. Identify the class of amine and explain its basicity compared to alcohols.
4. Medical Applications of Amines in Pharmacy
As an aspirant, connecting textbook chemistry to medical reality improves retention.
Analgesics: Amines like Morphine are essential for chronic pain management.
Antidepressants: Compounds like Amoxapine are nitrogen-based.
Water Purification: Amines are used in disinfecting drinking water and manufacturing herbicides.
5. Official Resources and Links
CBSE Official Academic Portal: cbseacademic.nic.in
Official Link : https://www.cbse.gov.in/cbsenew/question_bank.html
Conclusion
Mastering the CBSE Class 12 Chemistry Question Bank for Amines is a journey from understanding simple ammonia derivatives to complex medicinal chemistry. By focusing on named reactions, basicity trends, and the 2026 exam pattern, you can secure top marks in organic chemistry.
6. Frequently Asked Questions (FAQs)
Q1: What is the most important reaction in the CBSE Class 12 Chemistry Question Bank for Amines?
Ans: The Hoffmann Bromamide Degradation and Hinsberg’s Test are historically the most repeated. In the 2026 exam, expect at least one conversion or identification question involving these two.
Q2: How does the basicity of amines vary in gas phase vs. aqueous phase?
Ans: In the gas phase, basicity follows a simple +I effect: 3^circ > 2^circ > 1^circ. However, in the aqueous phase, hydration and steric hindrance play a role, making 2^circ amines generally the strongest.
Q3: Are diazonium salts stable?
Ans: Benzene diazonium chloride is stable only at low temperatures (0-5°C) and is used immediately. Aliphatic diazonium salts are highly unstable and decompose to form alcohols.
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