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HSC Biology Question Bank 2026: Important Questions for Human Health, Food Production, and Microbes

  • Feb 19
  • 3 min read

HSC Biology Question Bank 2026 cover. Text on white background, red and black colors. Topics: Human Health, Food Production, Microbes.


Preparing for the Maharashtra Board exams requires a strategic approach, especially for high-yield chapters like Human Health and Diseases, Enhancing Food Production, and Microbes in Human Welfare. With the 2026 HSC Biology exam scheduled for February 25, 2026, students must focus on the official HSC Biology Question Bank 2026 provided by SCERT Maharashtra to ensure they are aligned with the latest paper pattern.


These three chapters collectively contribute significantly to the 70-mark theory paper. By analyzing previous years' question papers (PYQs) from 2022 to 2025, we have identified recurring patterns, essential diagrams, and the medical applications most likely to appear in the 2026 examination.


HSC Biology Human Health and Diseases: High-Yield Medical Topics



This chapter is a cornerstone of the Biology syllabus, often featuring 3-mark and 4-mark questions related to pathology and immunology.


Most Repeated Questions (2022–2025)


  • Immunity Types: Differentiate between Innate and Acquired immunity, or Active and Passive immunity.


  • Structure of Antibody: A well-labelled diagram of an antibody molecule (Y-shaped protein) is a frequent 3-mark question.


  • Major Diseases: Descriptive questions on Malaria (Life cycle of Plasmodium), AIDS (Structure of HIV), and Cancer (Types of tumors and carcinogens).


  • Adolescence and Addiction: Impact of drug and alcohol abuse on the nervous system and liver health.


Important Medical Concepts for 2026


Medical entrance aspirants should pay close attention to the ELISA test (Enzyme-Linked Immunosorbent Assay) for HIV detection and the role of Interferons as anti-viral factors. Understanding the Rh factor and its clinical significance in pregnancy is also a must-know.


Enhancing Food Production: Strategy for Full Marks



This section focuses on the application of biological principles to meet the growing food demands of 2026. It bridges the gap between traditional farming and modern biotechnology.


Key Areas to Study


  • Plant Breeding Steps: Learn the five essential steps: Collection of variability, Evaluation, Cross-hybridization, Selection of recombinants, and Testing.


  • Tissue Culture: Definitions of Explant, Callus, Totipotency, and the advantages of Micropropagation.


  • Animal Husbandry: Focus on MOET (Multiple Ovulation Embryo Transfer) and the benefits of Inbreeding vs. Outbreeding.


  • Single Cell Protein (SCP): The use of microbes like Spirulina to provide high-quality protein.


Pro-Tip for 2026


Focus on Biofortification. Questions often ask for specific examples like Atlas 66 (high protein wheat) or Iron-fortified rice, as these are highly relevant to current global health initiatives.



Microbes in Human Welfare: The "Formula" for Success



While this chapter doesn't have mathematical formulas, it relies on "Biological Formulas"—the specific names of microbes and their corresponding products.


Microbial Product Table


Product

Microbial Source

Use/Application

Cyclosporin A

Trichoderma polysporum

Immunosuppressive agent

Statins

Monascus purpureus

Blood-cholesterol lowering agent

Streptokinase

Streptococcus

"Clot buster" for heart patients

Citric Acid

Aspergillus niger

Food preservative/flavoring


Sewage Treatment and Biogas


The 2026 exam is highly likely to include a question on the Secondary Treatment of Sewage (Biological Treatment). Understand the role of BOD (Biochemical Oxygen Demand) and how "flocs" reduce water pollution. For Biogas, practice the diagram of a typical anaerobic digester.


Official Links for Maharashtra Board Question Banks



The Maharashtra State Board of Secondary and Higher Secondary Education (MSBSHSE) and the State Council of Educational Research and Training (SCERT) release these resources to help students understand the "Examiner Mindset."




Note: Use these links only to download the official "Prashnapedhi" (Question Bank) and reference papers. Avoid third-party sites that may provide outdated or incorrect 2026 patterns.

Conclusion

Success in the 2026 HSC Biology exam depends on how well you balance theory with diagrammatic representation. By mastering the HSC Biology Question Bank 2026, you not only prepare for the board questions but also build a solid foundation for medical entrance exams. Focus on the microbes' names, the steps of food production, and the mechanisms of human immunity to ensure a top-tier result.



Frequently Asked Questions (FAQs)



Q1: Is the HSC Biology Question Bank 2026 enough to score above 90%? 


Ans: The HSC Biology Question Bank 2026 is an excellent resource for practice, but it should be used alongside the official textbook. Board exams often prioritize textbook-based definitions and diagrams.


Q2: Which diagrams are most important for the 2026 exam in these chapters? 


Ans: Focus on the Structure of an Antibody, the Biogas Plant, and the Life Cycle of the Malarial Parasite.


Q3: What is the weightage of "Human Health and Diseases" in 2026? 


Ans: Combined with "Enhancement of Food Production" and "Microbes," these chapters typically carry a weightage of 8 to 12 marks without options.


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